Revolugen Ltd

Revolutionary molecular tools for the extraction and simultaneous size selection of long-length DNA fragments

RevoluGen is a privately held scientific research and development company commercialising molecular tools with a specific focus on rapidly extracting long and pure DNA fragments from cells.

RevoluGen’s Nucleic Acid Isolation and Purification (NAIP) products have particular applications in delivering HMW-DNA in record time for long-read DNA sequencing as well many other nucleic acid applications. Fire Monkey significantly improves long-read sequencing results by extracting long-fragment DNA with minimal small-fragment DNA. Used independently, the Fire Flower size selection protocol can improve the molecular ratio of any extraction kit its output is compatible with all sequencing technologies.

With Fire Monkey and Fire Flower, the long-read DNA sequencing revolution starts with RevoluGen.

Key Highlights

Disruptive, cutting edge Fire Monkey technology can extract longer and purer DNA than existing methods in as little as one hour

Only technology that allows extraction and simultaneous size selection of long-length DNA fragments, which are critical for long-read DNA sequencing

Superior efficacy and accuracy validated on various sequencing platforms such as Oxford Nanopore, 10x Genomics, Illumina and PacBio

Automated protocol in development to enhance throughput and efficiency in order to reduce costs

Poised for substantial growth through commercial global distribution and manufacturing agreements with Merck KGaA and Cytiva

Multiple growth and expansion opportunities in infectious diseases, Antibiotic Microbial Resistance (AMR) and microbiome metagenomics

Commercialisation

RevoluGen’s products and technologies are based on molecular laboratory tools invented by our CSO Dr. Georgios Patsos. After six years of development and testing, and extensive validation with leading academic partners on leading DNA sequencing platforms, our patent protected Fire Monkey and Fire Flower products were launched in 2019 primarily for the extraction and purification of High Molecular Weight DNA (HMW-DNA) from cells. Our technologies are particularly good at extracting HMW-DNA that contains sufficient long DNA fragments to markedly improve long-read genomic sequencing.

Our strategy is to rapidly exploit the explosive growth opportunities for long-read DNA sequencing applications by expanding manufacturing and distribution, and by accelerating the development of automated protocols.

Partnerships

RevoluGen is headquartered in the UK, where we have R&D, manufacturing and direct customer sales and support. To facilitate widest global customer access, scale production and achieve automation, we have secured agreements with world-leading molecular biology tools companies.

2017